Author/Editor | Pokrajac, Tatjana; Gorenšek, Milan; Stefanovič, Milan; Juteršek, Albert; Pegan, Vladislav; Drenovec, Miran; Bratina, Radislav; Ljepovič, Liljana | |
Title | Dedne adenomatozne polipoze | |
Translated title | Hereditary adenomatous polyposis | |
Type | članek | |
Source | Endoskopska revija | |
Vol. and No. | Letnik 6, št. 15 | |
Publication year | 2001 | |
Volume | str. 147-57 | |
Language | slo | |
Abstract | This review article highlights the salient clinical features of the hereditary forms of colon cancer - the polyposis and non-polyposis syndromes - and their genetic basis. Such information not only provides insight into the molecular pathogenesis of colon cancer, but may also constitute a basis for genetic testing, detection, surveillance, and therapy of colon cancer. | |
Summary | V preglednem članku bomo predstavili klinični vidik dednih oblik karcinoma debelega črevesa - polipozni in nepolipozni sindrom - in njihovo gensko osnovo. Takšna informacija nam bo v pomoč ne samo za spoznanje molekularne patogeneze kolorektalnih karcinomov, temveč nam bo lahko temelj za uporabo genskih testov, odkrivanje, nadzor in zdravljenje karcinomov širokega črevesa. | |
Descriptors | ADENOMATOUS POLYPOSIS COLI COLORECTAL NEOPLASMS CHEMOPREVENTION ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS GARDNER SYNDROME |