Author/Editor     Pokrajac, Tatjana; Gorenšek, Milan; Stefanovič, Milan; Juteršek, Albert; Pegan, Vladislav; Drenovec, Miran; Bratina, Radislav; Ljepovič, Liljana
Title     Dedne adenomatozne polipoze
Translated title     Hereditary adenomatous polyposis
Type     članek
Source     Endoskopska revija
Vol. and No.     Letnik 6, št. 15
Publication year     2001
Volume     str. 147-57
Language     slo
Abstract     This review article highlights the salient clinical features of the hereditary forms of colon cancer - the polyposis and non-polyposis syndromes - and their genetic basis. Such information not only provides insight into the molecular pathogenesis of colon cancer, but may also constitute a basis for genetic testing, detection, surveillance, and therapy of colon cancer.
Summary     V preglednem članku bomo predstavili klinični vidik dednih oblik karcinoma debelega črevesa - polipozni in nepolipozni sindrom - in njihovo gensko osnovo. Takšna informacija nam bo v pomoč ne samo za spoznanje molekularne patogeneze kolorektalnih karcinomov, temveč nam bo lahko temelj za uporabo genskih testov, odkrivanje, nadzor in zdravljenje karcinomov širokega črevesa.
Descriptors     ADENOMATOUS POLYPOSIS COLI
COLORECTAL NEOPLASMS
CHEMOPREVENTION
ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL
COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS
GARDNER SYNDROME