Author/Editor     Maraspin, V; Ružić-Sabljić, E; Cimperman, J; Lotrič-Furlan, S; Jurca, T; Picken, RN; Strle, F
Title     Isolation of Borrelia burgdorferi sensu lato from blood of patients with erythema migrans
Type     članek
Source     Infection
Vol. and No.     Letnik 29, št. 2
Publication year     2001
Volume     str. 65-70
Language     eng
Abstract     Background: We assessed the isolation rate of Borrelia burgdorferi sensu lato from blood in European patients with typical erythema migrans and evaluated the course and outcome of their illness. Patients and methods: Adult patients diagnosed with erythema migrans and from whom borreliae cultured from blood were included in this study. Results: Borreliae were isolated from the blood of 35/2,828 (1.2%) patients, on average 7 days (range 1-47 days) after the appearance of erythema migrans. Only seven (20%) patients reported constitutional symptoms. 24/35 isolates were typed of which 20 were Borrelia afzelii and four were Borrelia garinii. 31 (88.6%) patients were treated with oral antibiotics while four (11.4%) received ceftriaxone iv. The course and outcome of the illness were favorable in all patients. Conclusion: In European patients with erythema migrans the yield of blood culturing was low, spirochetemia was often clinically silent and the course and outcome of the illness were favorable; the predominantly isolated strain was B. afzelii.
Descriptors     LYME DISEASE
ERYTHEMA CHRONICUM MIGRANS
BORRELIA BURGDORFERI
PROGNOSIS
TREATMENT OUTCOME
ANTIBIOTICS
CEFTRIAXONE
CEPHALOSPORINS
AGE FACTORS