Author/Editor		Cokan, Andreja; Vujkovac, Bojan; Slemenik-Pušnik, Cirila; Kotnik, Jožica
Title		Meningokokna sepsa - prikaz primera
Translated title		Meningococcal sepsis - case report
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 71, št. 1
Publication year		2002
Volume		str. 15-8
Language		slo
Abstract		Background. Fulminant meningococcemia is a rare but severest manifestation of infection with Neisseria meningitidis. Despite the most advanced treatment the death rate remains between 30-70%. Usually, it occurs in children, while immune system deficiencies are frequently discovered in elderly patients. The incidence of meningococcal infections in Slovenia is about 0.43/100,000 inhabitants and 4.1 % of these are in the form of fulminant meningococcal sepsis. Patients and methods. The paper describes the case of a 17 year-old patient with fulminant meningococcal sepsis, which he had already recovered from once before as a child. According to the prognostic factors, the expected mortality was above 75%. Continuous dialysis was implemented in addition to conventional treatment. The patient died due to central nervous system involvement after 10 days. Conclusions. We propose that the described treatment succeeded in slowing the expected fulminant course of the disease. A disturbance in the patient's immune system was demonstrated and Neisseria meningitidis W-135 was isolated.
Summary		Izhodišča. Fulminantna meningokokna sepsa je redka in najhujša oblika okužbe z Neisserio meningitidis. Kljub najsodobnejšemu zdrav jenju je smrtnost še vedno od 30 do 70-odstotna. Običajno zbolijo otroci, pri starejših obolelih pa pogosto ugotovimo motnje v njihovem imunskem sistemu. V Sloveniji je incidenca meningokoknih okužb okoli 0, 43/ 100.000 prebivalcev, okoli 4,1 % teh okužb pa poteka v obliki fulminantne meningokokne sepse. Bolniki in metode. V prispevku opisujemo primer 17-letnega bolnika s fulminantno meningokokno sepso, ki jo je že enkrat prebolel v otroštvu. Glede na prognostične tabele je bila pričakovana smrtnost nad 75%. V zdravljenju smo poleg običajnega zdravljenja uporabili tudi kontinuirane metode dialize. Bolnik je po 10 dneh zdravljenja umrl zaradi prizadetosti osrednjega živčnega sistema. Zaključki. Z opisanim zdravljenjem menimo, da smo uspeli upočasniti pričakovani fulminantni potek bolezni. Dokazali smo motnjo v imunskem sistemu bolnika in osamili sev N. meningitidis W-135.
Descriptors		SEPSIS NEISSERIA MENINGITIDIS MENINGOCOCCAL INFECTIONS ADOLESCENCE