Author/Editor		Syrjaenen, Kari J; Eržen, Mojca; Costa, Silvano
Title		Histological and quantitative pathological prognostic factors in cervical cancer
Type		članek
Source		CME J Gynecol Oncol
Vol. and No.		Letnik 6
Publication year		2001
Volume		str. 279-301
Language		eng
Abstract		A substantial amount of work aiming to elucidate the prognostic factors in cervical carcinoma has been done using the histopathological assessment of the tumour specimens, either by conventional descriptive or semiquantitative (grading) approaches or adopting the techniques of quantitative pathology (morphometric and stereological measurements). In principle, the prognostic factors can be divided into two major categories: 1. factors of the tumour origin, and 2. those of the host origin. These concepts are regularly referred to as tumour-host (inter)relationships, and these morphological manifestations of tumour-host reactions represent the first attempts to get insights in tumour immunology. After almost two decades of intense studies using immunohistochemical techniques with a bewildering repertoire of biological tumour markers, many of the factors regulating the biological behaviour of cervical carcinoma are incompletely or purely understood, and undoubtedly, histopathology and related morphological methods still have an important role in the assessment of the prognostic factors in this disease.
Descriptors		CERVIX NEOPLASMS NEOPLASM STAGING PROGNOSIS AGE FACTORS CARCINOMA, SQUAMOUS CELL ADENOCARCINOMA