Author/Editor		Kuder, Lucija; Vlaisavljević, Veljko; Reljič, Milan; Gavrić-Lovrec, Vida
Title		Pomen ultrazvočnih značilnosti endometrija pri napovedovanju vgnezditve zarodkov v postopkih zunajtelesne oploditve v naravnem ciklusu
Translated title		Predictive value of the echographic characteristics of endometrium on implantation rate in in-vitro fertilization in unstimulated cycle
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 71, št. Suppl 1
Publication year		2002
Volume		str. I-31-4
Language		slo
Abstract		Background. The purpose of this study was to determine whether endometrial features such as thickness, type and subendometrial movements observed by ultrasound on the day of embryo transfer in in vitro fertilisation (NF) in natural cycles, can predict implantation outcome. Methods. One hundred and eight natural IVF cycles in which the embryo transfer was performed were included in a prospective study. One hour prior to embryo transfer vaginal ultrasound examination was done to measure endometrial thickness, asses endometrial pattern and movements. The thickness and the type of endometrium were estimated in sagital plane of the uterus. Estimations of the direction of movements, amplitude and the amount of waves regarding the length of uterine cavity were performed. Women were divided into two groups: the first group consisted of those who conceived and the second of those who did not Results. The average age of women was 32.8 +- 4.07 years. Both groups were comparable in terms of age, estradiol level and average follicle diameter on the day of hCG application. Pregnancy rate on embryo transfer being 22.2% (24/108), and 84 women (77.8%) did not conceived. The thickness, type and endometrial movements were similar in both groups, therefore, not statistically significant (p > 0.05). Duration of menstrual cycles prior to hCG application in no concived group was shorter, statistically significant (p = 0.002). Conclusions. On the basis owing to ultrasound characteristics such as subendometrial movements, thickness and pattern on the day of embryo transfer in the natural IVF/ICSI cycle have no predictive value of embryo implantation.
Summary		Izhodišča. Namen raziskave je bil ugotoviti, ali z ultrazvočnimi značilnostmi endometrija, kot so debelina, tip in gibanje subendometrija na dan prenosa zarodka v postopkih zunajtelesne oploditve (IVF) v naravnem ciklusu lahko napovemo možnost vgnezditve zarodka. Metode dela. V prospektivno raziskavo smo vključili 108 naravnih ciklusov IVF, pri katerih je prišlo do prenosa zarodka. Eno uro pred prenosom zarodkov smo z vaginalnim ultrazvokom merili debelino endometrija, ocenjevali izgled in gibanje endometrija. Debelino in tip endometrija smo ocenjevali v sagitalni ravnini uterusa. Ocenili smo smer gibanja, amplitudo in obseg valovanja glede na dolžino maternične votline. Ženske smo razdelili v dve skupini: prvo skupino so tvorile tiste, ki so zanosile, in drugo tiste, ki niso. Rezultati. Povprečna starost žensk je bila 32,8 +- 4,07 leta. Obe skupini sta bili primerljivi po starosti, bazalnih vrednostih FSH, serumski koncentraciji estradiola in povprečnem premeru folikla na dan dajanja hCG. Stopnja zanositve na prenos zarodka je bila 22,2% (24/108), 84 (77,8%) žensk pa ni bilo nosečih. Debelina in tip endometrija ter smer, obseg in amplituda gibanja endometrija so bili podobni v obeh skupinah in se statistično pomembno niso razlikovali (p > 0,05). Trajanje menstruacijskega ciklusa pred dajanjem hCG v skupini nenosečih je bilo statistično pomembno krajše (p = 0, 002). Zaključki. Na osnovi ugotavljanja ultrazvočnih značilnosti endometrija, kot so debelina in tip ter gibanje na dan prenosa zarodka v postopku zunajtelesne oploditve v naravnem ciklusu ne moremo predvideti možnosti vgnezditve zarodka.
Descriptors		FERTILIZATION IN VITRO EMBRYO TRANSFER ENDOMETRIUM FSH ESTRADIOL GONADOTROPINS, CHORIONIC OVULATION INDUCTION PREGNANCY