Author/Editor		Stiller, CA; Stevens, MCG; Magnani, C; Corazziari, I; Pompe-Kirn, V
Title		Survival of children with soft-tissu sarcoma in Europe since 1978: results from the EUROCARE study
Type		članek
Source		Eur J Cancer
Vol. and No.		Letnik 37, št. 6
Publication year		2001
Volume		str. 767-74
Language		eng
Abstract		Soft-tissue sarcomas account for 5-8% of all childhood cancers in European countries. In the EUROCARE childhood cancer study, there were 2163 registrations from 17 countries for soft-tissue sarcomas in patients aged 0-14 years during 1978-1989. Of this total, three-quarters were contributed by childhood cancer registries in Germany and the UK. Age-standardised 5-year survival rates of children diagnosed during 1985-1989 were 65% (95% confidence interval (CI) 56-72) for rhabdomyosarcoma, 68% (95% CI 58-77) for fibrosarcoma, 78% (95% CI: 64-87) for other specified soft-tissue sarcomas except Kaposi's and 51% (95% CI 3765) for 'unspecified' soft-tissue sarcomas. Survival rates increased steadily throughout the 12-year study period for all soft-tissue sarcomas combined, but the increase took place predominantly in the early 1980s for rhabdomyosarcoma. Improvements in survival which had previously been reported from individual countries and in clinical series are confirmed as having taken place throughout much of Europe on a population basis. In a supplementary analysis, there was little indication of a further improvement during 1990-1992.
Descriptors		SARCOMA FIBROSARCOMA RHABDOMYOSARCOMA CHILD AGE FACTORS SEX FACTORS SURVIVAL RATE EUROPE REGISTRIES PROPORTIONAL HAZARDS MODELS MULTIVARIATE ANALYSIS