Author/Editor		Klanjšček, Ana; Medved, Ana
Title		Nenadna nepričakovana smrt dojenčkov
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2001
Volume		str. 51
Language		slo
Abstract		Background The research analyses the problem of the sudden unexpected death in infancy (SUDI) in a sample of infants who were autopsied at the Institute of Forensic Medicine, Faculty of Medicine, University of Ljubljana, in the decade 1990 - 99. The aim of our research is to determine causes of death of infants who died suddenly, to examine risk factors for SUDI and to confirm the triple - risk model of the sudden infant death syndrome (SIDS). Hypothesis: At autopsy of infants who died suddenly, pathologists mostly find inflammatory changes in the respiratory tract. Autopsy findings can be also non - specific. SUDI is related to infant, maternal and social risk factors. The triple - risk model supports the explanation of SIDS. Methods: On the sample of infants who died suddenly, we analysed the age at death, the month and the day of death, the dynamics of physical development from birth to death, the anamnesis of events immediately before death and the autopsy diagnoses. Risk factors for SUDI were assessed by a retrospective epidemiologic "case - control" study. We studied three concepts of the triple - risk model of SIDS: a vulnerable infant, a critical developmental period and exogenous stressors. RESULTS: Infants died of SUDI mostly at the age of one to four months (70.36%), in autumn and winter (59,21%), at weekends (the weekend ratio is 2.00). Stagnation of physical development occured in 37.0% of infants. By anamnesis, 48.15% of infants were entirely healthy before death. Respiratory tract infections were the cause of death in the majority of infants (63%). Strong risk factors (the relative risk is 2.6 or higher) for SUDI are: small for gestational age, gestational age less than 37 weeks, maternal age 35 years or more, multipara (More than three parturitions), lone mother, lower-eduaction mother (primary school or less), maternal smoking during prgnancy and less than five prenatal visits. (Abstract truncated at 2000 characters).
Descriptors		SUDDEN INFANT DEATH AUTOPSY CAUSE OF DEATH INFANT CASE-CONTROL STUDIES AGE FACTORS SEASONS CHILD DEVELOPMENT GESTATIONAL AGE RESPIRATORY TRACT INFECTIONS RISK FACTORS