Author/Editor		Kermavnar, Melita T
Title		Motnje srčnega ritma pri testu z nagibno mizo in nitroglicerinom
Translated title		Arrhythmias in head-up tilt table test
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2000
Volume		str. 28
Language		slo
Abstract		Introduction. Syncope is defined as a transient loss of consiousness and postural tone caused by sudden decrease of cerebral blood flow. The most frequent form is neurocardiogenic or vasovagal syncope, characterized by hypotension and bradycardia. In the past there have been a lot of difficulties diagnosing this form of transitient loss of consiousness. Until recently most of the neurocardiogenic syncope were classified as syncope of unknown origin, but with the use of head-up tilt table test (HUT) 50-60% of these syncope were proven to be neurocardiogenic in origin. HUT is a safe noninvasive test, which can be potentiated with sublingual nitroglycerine to obtain a larger positivity rate. With higher number of positive test results we also expect a larger number of arrhythmias in the form of extrasystole or even asystolia, but the question remains: is nitroglycerine provoked HUT potentionally more harmful for the patient. Patients and methods. We compared a group of 565 patients (group A) who were tested with passive HUT to a group of 546 patients by whom HUT was potentiated with sublingual nitroglycerine. We used a HUT protocol, which was previously described by Fitzpatrick et al. First 10 minutes of supine position were followed by 45 minutes of passive tilt at 60*. Patients in group B were given 0,5 mg of nitroglycerine (Angisedž) sublingually in the 30. minute of test. During the test we recorded a onechannel ECG with surface electrodes, and with mercury sfingomanometer blood pressure. On the ECG record we analysed arrhythmias that occurred during the test and subgrouped these arrhythmias acording to the time in which they appeared: predominantly before the administration of nitroglycerine, predominantly after the administration of the drug or indifferently through the whole test. We defined the specifity and sensitivity of HUT for both groups. Results were compared using the chi2test and Student t-test. (Abstract truncated at 2000 characters).
Descriptors		ARRHYTHMIA NITROGLYCERIN TILT-TABLE TEST SUPINE POSITION ELECTROCARDIOGRAPHY SYNCOPE, VASOVAGAL