Author/Editor     Kermavnar, Melita T
Title     Razmerje med aktivnostjo simpatika in parasimpatika pri testu z nagibno mizo
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta
Publication year     2001
Volume     str. 57
Language     slo
Abstract     Introduction. Neurocardiogenic syncope is the most frequent transitional loss of consciousness, which is caused by inappropriate triggering of Bezold-Jarisch reflex. The triggering agent is most commonly the upright posture. With the help of spectral analysis technicque, the researcers demonstrated, that there is a large increase in sympathetic activity just before syncope, but at the point of syncope a paradox inhibiton of this activity occurs with consequent vasodilatation and bradycardia, which result in loss of consciousness. In our study we wanted to find out whether the autonomic nervous system activity differences exist between patients and controls in response to head-up tilt table testing, and whether these differences are larger in tilt table test with nitroglycerine. Subiects and methods. We compared a group of 30 subjects, who recieved nitroglycerine during the test (NTG+), to a group of 30 subjects who were tested without nitroglycerine (NTG-). In half of patients of each group syncope occured during the test (SIN+) and in the other half it did not (SIN-). With spectral analysis of heart rate variability we determined the ratio between medium- (SF) and highfrequency (VF) bands (SFIVF) which represents the balance between sympathetic and parasympathetic nervous systems. In addition we measured the mean heart rate in different phases of the test. The results were compared with t test for dependant samples for changes within each group and with Student t test for comparisson between groups. Statistically signifficant difference was p < 0,05. (Abstract truncated at 2000 characters)
Descriptors     TILT-TABLE TEST
SYMPATHETIC NERVOUS SYSTEM
PARASYMPATHETIC NERVOUS SYSTEM
SYNCOPE, VASOVAGAL
HEART RATE
NITROGLYCERIN
SUPINE POSITION