Author/Editor		Šibanc, Branko; Lešničar, Gorazd; Tratar, Franci
Title		Rezultati nadzorovanega protimikrobnega zdravljenja v Splošni bolnišnici Celje 1995-2000
Translated title		Results of controlled antimicrobial treatment at the Celje General hospital between 1995-2000
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 41, št. Suppl 2
Publication year		2002
Volume		str. 53-9
Language		slo
Abstract		In the paper, the usage of antimicrobials at the Celje General Hospital between 1995 and 2000 is analyzed. During this period, the usage of antibacterial drugs for systemic use, expressed as the defined daily dose per 100 bed days (DDD/100 BD), increased from 50.73 DDD/100 BD in 1995 to 68.84 DDD/100 BD in 2000. The antibiotic group that showed the greatest increase in use was J01C (penicillins). The usage of cephalosporins gradually decreased overall, but there were differences in the relative use of different individual groups. An increase was observed in the usage of first- and second-generation cephalosporins, while the usage of third-generation cephalosporins decreased. The usage of fluoroquinolones and macrolides increased gradually throughout the study period, while the usage of aminoglycosides decreased. More intensive treatment and patients whose health has been more severely compromised might be possible explanations for increased usage of antimicrobials.
Summary		Analizirali smo porabo protimikrobnih zdravil v Splošni bolnišnici Celje v obdobju od 1995 do 2000. V tem času je poraba antibiotikov, izražena v dnevnih definiranih odmerkih na sto bolnišnično oskrbnih dni (DDD/100 BOD), porasla s 50,73 DDD/100 BOD na 68,84 DDD/100 BOD. Porast je predvsem posledica višje porabe penicilinov skupine J01C. Poraba cefalosporinov je globalno upadla, vendar različno glede na generacijo. Tako smo ugotavljali porast porabe cefalosporinov prve in druge generacije ter zmanjšanje porabe cefalosporinov tretje generacije. V opazovanem obdobju smo zaznali stalen porast porabe fluorokinolonov in makrolidov ter zmanjšano porabo aminoglikozidov. Večja poraba protimikrobnih zdravil je morda tudi posledica krajše bolnišnične oskrbe težjih bolnikov.
Descriptors		BACTERIAL INFECTIONS ANTIBIOTICS DRUG UTILIZATION HOSPITALS, GENERAL