Author/Editor		Pretnar-Oblak, Janja; Miloševič, Zoran; Popović, Mara
Title		Diagnostika primarnih limfomov osrednjega živčevja
Translated title		The diagnosis of the primary central nervous system lymphoma
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 71, št. 5
Publication year		2002
Volume		str. 293-8
Language		slo
Abstract		Background. Primary central nervous system lymphoma (PCNSL) is an uncommon tumour that arises within and is confined to the central nervous system. The incidence of PCNSL is increasing among immunocompromised patients as well as among normal older population. Clinical features and changes of the cerebrospinal fluid (CSF) are non-specific. The diagnosis of PCNSL is based primarily on neuroimaging, biopsy and histopathology. Conclusions. In our article we present three patients with PCNSL in whom the correct diagnosis was established only post mortem. We also present a patient in whom we suspected PCNSL. based on clinical features and CSF changes. However the biopsy reveiled a glioblastoma.
Summary		Izhodišča. Primarni limfom osrednjega živčevja (PLOŽ) je redek tumor, ki vznikne v osrednjem živčevju (OŽ) in je nanj omejen. Pogostnost tumorja se v zadnjih dveh desetletjih veča tako pri imunsko oslabelih kot imunsko normalno odzivnih starejših ljudeh. Klinični znaki in simptomi kot tudi spremembe v likvorju so neznačilne. Diagnoza PLOŽ sloni na slikovnem prikazu sprememb v OŽ, biopsiji in mikroskopskem pregledu bioptičnega vzorca. Zaključki. V prispevku predstavljamo tri bolnike, pri katerih smo diagnozo PLOŽ postavili šele po smrti. Predstavljamo tudi bolnico, pri kateri smo glede na izvid slikovnih preiskav, predvsem pa na podlagi izvida, posumili na PLOŽ, biopsija možganov pa je razkrila glioblastom.
Descriptors		CENTRAL NERVOUS SYSTEM NEOPLASMS LYMPHOMA AGED TOMOGRAPHY, X-RAY COMPUTED