Author/Editor		Vodopivec-Jamšek, Vlasta
Title		Priprava bolnikov, ki prejemajo antikoagulacijska zdravila, na načrtovani operativni poseg
Translated title		Management of patients on anticoagulation drugs before and after elective surgery
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 41, št. Suppl 1
Publication year		2002
Volume		str. 67-72
Language		slo
Abstract		The most common indications for anticoagulation therapy which are specifically important in family medicine are atrial fibrillation, the presence of a mechanical heart valve and venous thromboembolism. Treatment with warfarin presents a problem if patients with these indications need surgery, because the interruption of anticoagulation increases the risk of thromboembolism. The paper presents the thrombosis risk of stopping anticoagulation in specific settings, bleeding risks of certain procedures and warfarin and heparin pharmacokinetics. Recommendations are discussed regarding management of patients on anticoagtzlants who undergo invasive procedures.
Summary		Najpogostejše indikacije za antikoagulacijsko zdravljenje, ki so še posebej pomembne za zdravnika družinske medicine, so kronična atrijska fibrilacija, umetne mehanske srčne zaklopke in venska tromboza. Zdravljenje z varfarinom predstavlja problem, če bolniki s temi stanji potrebujejo operativni poseg, ker se ob prekinitvi antikoagulacijskega zdravljenja poveča tveganje za trombembolične dogodke. Predstavljeno je tveganje za trombembolične dogodke med prekinitvijo antikoagulacije pri posebnih stanjih, tveganje za krvavitve ob nekaterih posegih in farmakokinetika varfarina in heparinov. Prikazani so tudi nekateri možni načini vodenja antikoagulacijskega zdravljenja v obdobju ob operaciji.
Descriptors		ANTICOAGULANTS PREOPERATIVE CARE THROMBOPHLEBITIS THROMBOEMBOLISM POSTOPERATIVE COMPLICATIONS RISK FACTORS HEART VALVE PROSTHESIS ATRIAL FIBRILLATION HEMORRHAGE WARFARIN HEPARIN