Author/Editor		Vidmar-Kocijančič, Ksenija
Title		Pomen ultrazvočno vodene tankoigelne biopsije povečanih nadledvičnih žlez pri bolnikih s pljučnim rakom
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2002
Volume		str. 46
Language		slo
Abstract		The adrenal gland represents one of the most frequent sites of metastasis in patients with lung cancer. Adrenals are not easily accessible by biopsy owing to ditticult approach. Therefore information about the accuracy and safety of US-guided aspiration biopsies is very scarce. Most of the authors prefer CT-guided biopsies over US-guided although no comparative studies between those two modalities have been done so far. This study was designed to compare the accuracy and safety of US-guided versus CT-guided aspiration biopsies in patients with lung cancer. Cytology results were used to determine the probability of benign lesion within adrenal gland in patient with lung cancer. Routes of metastatic spread to the adrenal gland were also studied. From January 1991 to December 2000 thirtytwo patients with histologically proven lung cancer underwent US-guided adrenal aspiration biopsy at the Institute of Oncology Ljubljana. Basic demographic data as well as information on the primary lung cancer type were obtained from medical charts. Safety and accuracy of US-guided aspiration biopsies were evaluated. In order to analyze the possible mode and pathways of adrenal metastases from lung cancer, the frequency of adrenal metastases (ipsilateral and contralateral to the site of primary cancer) was investigated based on cytology results. Statistical analysis was performed using appropriate statistical tests. US-guided aspiration biopsy turned out to be accurate in more than 90% cases, and very safe. In 13%, isolated adrenal masses found in cancer patients at primary staging were adenomas. This percentage was much lower in patients having an adrenal mass found during follow-up. Mean survival of surgically treated patients was 4 years and of non-surgical patients approximately 5 months. (Abstract truncated at 2000 characters).
Descriptors		LUNG NEOPLASMS ADRENAL GLAND NEOPLASMS NEOPLASM STAGING BIOPSY, NEEDLE SURVIVAL ANALYSIS RETROSPECTIVE STUDIES