Author/Editor		Mekicar, Jernej
Title		Uporabnost računalniške analize pri predoperativnem odločanju za razširjeno limfadenektomijo pri raku želodca: evalvacija računalniškega programa Winestimate 2.5
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2001
Volume		str. 52
Language		slo
Abstract		BACKGROUND. Gastric carcinoma is one of the most frequent malignancy of the gastrointestinal tract and is an important cause of death in malignant diseases. Surgery is for now the only successful way of treatment. The goal of treatment is R0 resection with appropriate lymphadenectomy. Because at present technology can't predict sufficiently accurate the metastases in regional lymph nodes, the decision for appropriate lymphadenectomy stays in the hands of the surgeon. To ease the decision of the surgeon and to improve patients chance for survival some researcher have developed computer programs that analyses data from a data base of patients and predict survival time and lymph node metastases in an observed patient. One of the most quoted computer program for gastric carcinoma Estimate was developed in year 1984 by prof.dr. Keiichi Maruyama, M.D., from the National Cancer Center Hospital in Tokyo. AIM. Aim of the study was to evaluate the accuracyr of data given by the computer program WinEstimate v. 2.5 for prediction of survival time and lymph node metastases in Slovenian patients and if the computer program is good for making preoperative decisions in guiding the surgeon to proper lymph node dissection in observed gastric cancer patients. HYPOTHESIS. Hypothesis were: 1.) 5 year survival time of Slovenian group of patients who had R0 resection with D2 lymphadenectomy is the same as the survival of the Japanese group of patients that were used as a data base for the computer program WinEstimate 2.5. 2.) The computer prediction for lymph node metastases is matching the actual state. METHODS. In the study were included patients with gastric cancer who had R0 resection with D2 lymphadenectomy and the pathologist examined at least 15 lymph nodes in the resected material. (Abstract truncated at 2000 characters).
Descriptors		STOMACH NEOPLASMS LYMPH NODE EXCISION PROGNOSIS PREDICTIVE VALUE OF TESTS SURVIVAL ANALYSIS LYMPHATIC METASTASIS BAYES THEOREM DIAGNOSIS, COMPUTER-ASSISTED JAPAN SLOVENIA