Author/Editor		Fidler, Nataša; Sauerwald, Thorsten; Demmelmair, Hans; Koletzko, Berthold
Title		Biološka razpoložljivost dokozaheksaenojske kisline pri doječih materah
Type		članek
Source		In: Florjančič U, Musar A, editors. Raziskovalno delo podiplomskih študentov v Sloveniji - novo tisočletje: naravoslovje in tehnika. Ljubljana: Društvo mladih raziskovalcev Slovenije,
Publication year		2001
Volume		str. 411-20
Language		slo
Abstract		Docosahexaenoic acid (DHA) is important for growth and development of infants. We aimed at investigating the transfer of DHA and other fatty acids from the diet into the human milk. Starting four weeks post partum, ten lactating women consumed for 14 days either an oil rich in DHA (DHASCOTM, 200 mg DHA/day) (n=5) either a placebo oil (n=5). On the study day 14 all mothers consumed 2 mg 13C labelled DHASCOTM/kg body weight. Samples of milk were collected before and during 48 hours after the tracer ingestion. Fatty acid composition of milk was determined by GC and the 13C isotopic enrichments of milk fatty acid by GC-C-IRMS. After the DHA supplementation the DHA content of milk lipids from the supplemented group was higher than from the placebo group (0.37 vs. 0.21 wt.%, median, p=0.003). Transfer ofdietary 13C labelled palmitic, oleic acid and DHA into human milk during 48 hours after ingestion was similar. Notable lower recovery was observed for 13C labelled myristic acid (p<0.001). We conclude that maternal dietary intake of DHA is a major determinant of its content in milk lipids.'The transfer of DHA from the diet into human milk is comparable to that of palmitic and oleic acids.
Descriptors		LACTATION MILK, HUMAN FATTY ACIDS DIETARY FATS DOCOSAHEXAENOIC ACIDS SPECTRUM ANALYSIS, MASS BODY MASS INDEX