Author/Editor		Koren, Aleš
Title		Magnetic resonance spectroscopy: an overview of the method and its application in clinical neuroradiology
Translated title		Magnetna resonančna spektroskopija. Pregled metode in njena uporaba v klinični neuroradiologiji
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 36, št. 2
Publication year		2002
Volume		str. 95-102
Language		eng
Abstract		Background. Magnetic resonance spectroscopy (MRS) is a comparatively new diagnostic method. Brain tissue is very suitable for MRS analysis. In practice, only a small number of compounds present in the brain may be analysed by MRS. The utility of MRS in neuroradiology and clinical practice is constantly growing since the investigation is of help in the differential diagnosis of pathological processes as well as in assessing the progress of a disease and evaluating the outcome of treatment. In analysing the data obtained, a number of factors that may influence the objectivity of the result must be taken into account. The magnetic resonance scanner located at the Institute of Radiology, University Medical Centre Ljubljana, utilises modern MRS protocols and has proved a valuable tool in the diagnostic evaluation of neurologic diseases. Conclusions. MRS provides spectral analysis of substance in a selected volume of tissue, thereby offering an insight into the metabolic state of the tissue.
Summary		Izhodišča. Magnetno resonančna spektroskopija (MRS) je sorazmerno nova diagnostična metoda. Možganovina je zelo primerno tkivo za te vrste analizo. V praksi pa je z MRS mogoče analizirati le majhno število sestavin, ki so v možganskem tkivu. Uporabnost metode v neuroradiologiji in pri kliničnem delu narašča, saj pomaga tako pri diferencialni diagnostiki patoloških procesov kot pri opredelitvi progresije bolezni oz. uspeha terapije. Pri analizi rezultatov preiskave je potrebno upoštevati številne dejavnike, ki lahko vplivajo na objektivnost izvida. Magnetno resonančni tomograf na kliničnem inštitutu za radiologijo v KC v Ljubljani omogoča sodobne MRS protokole, ki jih uporabljamo v diagnostiki nevroloških in drugih bolezni. Zaključki. MRS omogoča spektralno analizo snovi v izbranem volumnu tkiva in s tem vpogled v njegovo metabolno stanje.
Descriptors		NUCLEAR MAGNETIC RESONANCE CENTRAL NERVOUS SYSTEM DISEASES NEURORADIOGRAPHY ADULT