Author/Editor | Dolenc-Grošelj, Leja; Vodušek, David B | |
Title | The importance of HLA DQB1*0602 typing in Slovene patients with narcolepsy | |
Type | članek | |
Source | Cell Mol Biol Lett | |
Vol. and No. | Letnik 7, št. 2 | |
Publication year | 2002 | |
Volume | str. 359-60 | |
Language | eng | |
Abstract | The HLA class II region genes DQB 1 *0602 and DQA 1 *0102 are currently the best genetic predictors for narcolepsy in humans (1). The aim of this study was to identify the HLA DQ alleles (DQB 1 *0602 and DQA 1 *0102) in Slovene sporadic narcoleptic patients. 11 patients who fulfilled ICSD criteria for narcolepsy entered the study. DRB 1 *1501 DQB 1 *0602 was present in all the patients while DQA1 *0102 was absent in 2 patients. We propose that DQB 1 *0602 typing is important in diagnosing narcolepsy in Slovene patients. | |
Descriptors | NARCOLEPSY HLA-DQ ANTIGENS ALLELES HISTOCOMPATIBILITY TESTING |