Author/Editor		Pavčnik, Dušan; Uchida, Barry T; Timmermans, Hans A; Corless, Christhoper L; O'Hara, Michael; Toyota, Naoyuki; Moneta, Gregory L; Keller, Frederick S; Roesch, Josef
Title		Percutaneous bioprosthetic venous valve: a long-term study in sheep
Type		članek
Source		J Vasc Surg
Vol. and No.		Letnik 35, št. 3
Publication year		2002
Volume		str. 598-602
Language		eng
Abstract		A long-term evaluation of a new percutaneously placed bioprosthetic, bicuspid venous valve (BVV) consisting of a square stent and small intestinal submucosa (SIS) covering was performed in 12 sheep. Of 26 BVVs placed into the jugular veins, 25 exhibited good valve function on immediate venography and 22 on venograms obtained before the sheep were killed. Gross and histologic examination results demonstrated incorporation of remodeled and endothelialized SIS BVVs into the vein wall. Slight to moderate leaflet thickening was found mostly at their bases. Percutaneously placed SIS BVV is a promising one-way, competent valve that resists venous back-pressure while allowing forward flow.
Descriptors		BIOPROSTHESIS BLOOD VESSEL PROSTHESIS JUGULAR VEINS SURGICAL INSTRUMENTS EQUIPMENT SAFETY FOLLOW-UP STUDIES DISEASE MODELS, ANIMAL PHLEBOGRAPHY PROSTHESIS DESIGN SHEEP TIME FACTORS TREATMENT OUTCOME VASCULAR PATENCY