Author/Editor     Vlaisavljević, Veljko; Kovačič, Borut; Reljič, Milan; Gavrić-Lovrec, Vida; Čižek-Sajko, Mojca
Title     Results of intracytoplasmic sperm injection of single oocyte in 362 unstimulated cycles
Type     članek
Source     J Assist Reprod Genet
Vol. and No.     Letnik 19, št. 3
Publication year     2002
Volume     str. 127-31
Language     eng
Abstract     Purpose: The purpose was to test the adequacy of unstimulated cycles for intracytoplasmic sperm injection (ICSI) and to evaluate implantation and pregnancy rates in three different age groups. Methods: ICSI was performed in 362 unstimulated cycles in women up to 45 years old. All cycles were monitored by serum estradiol, urinary LH, and ultrasound. Results: The delivery rate per started cycle was higher in patients younger than 36 (9.4%) than in cycles with patient's age between 36 and 39 years (4.8%) or older than 40 (4.6%) but the difference was not statistically significant. In all groups, the fertilization rate was similar (70.4, 77.6, and 84.8%, respectively). The pregnancy rate per cycle and the pregnancy rate per puncture was similar in the group of patients in age between 36 and 39 years (8.3 and 9.7%) and those older than 40 (7.7 and 9.3%). Conclusions: Unstimulated cycles monitored by serum estradiol, urinary LH, and ultrasound can produce an acceptable pregnancy rate after ICSI procedure only in patients younger than 36.
Descriptors     FERTILIZATION IN VITRO
OOCYTES
SPERMATOZOA
SPERM-OVUM INTERACTIONS
EMBRYO TRANSFER
ESTRADIOL
LH
OVARY