Author/Editor		Burja, Silva
Title		Procjena vrijednosti ultrazvučne pretrage u dijagnostici i pračenju ishoda ranog oštećenja mozga s naročitim osvrtom na praćenje procesa plastičnosti mozga
Type		monografija
Place		Zagreb
Publisher		Sveučilište u Zagrebu, Medicinski fakultet
Publication year		2002
Volume		str. 215
Language		cro
Abstract		The aim to this study was to find and determine diagnostic and prognostic value of ultrasound bain investigations in the group of risk new-borns eith different gestational ages for prediction of the abnormal neurological and cognitive development of child at the age of two years. Our results confirm significantly high prognostic value of definitely pathologic ultrasound finding. The comparison of diagnostic reliability of ultrasound brain investigation between the groups of new-borns with different gestational ages is very interesting and shows the highest reliability in the group of risk new-borns with the lowest gestational age. The ultrasound brain investigation has also high value for predicting abnormal development of child at the age of two in the group of term new-borns with certain pathologic ultrasound findings. Results of statistical analysis (method of multivariate logistic regression) show that definitely pathologic findings of ultrasound brain investigations are the most significant risk factors for abnormal development with cerebral palsy and disturbances in development of cognitive functions. Similar are conclusions of some recent studies of Norwegian authors about the role of the perinatal risk factors for the development of cerebral palsy. The ultrasound brain investigation of new-born at risk for later neurological abnormality has to be done in first four days after birth and has to be repeated according to pathology. With scheduled and carefully made ultrasound brain investigation of new-born, outlook of lesion can be precisely described and with help of perinatal history, etiopathogenesis of early brain damage sometimes can be econstructed. Towsend and co-workers in their recently published study also recommended ultrasound brain investigation of premature newborns with different risks for impairment of neurological functions at the age of 1 month. (Abstract truncated at 2000 characters)
Descriptors		CEREBRAL HEMORRHAGE NEURONAL PLASTICITY CEREBRAL ISCHEMIA BRAIN INJURIES INFANT, NEWBORN INFANT INFANT, PREMATURE HISTOCYTOCHEMISTRY IMMUNOHISTOCHEMISTRY GESTATIONAL AGE