| Author/Editor | Benoit, Evelyne; Mattei, Cesar; Ouanounou, Gilles; Meunier, Frederic A; Šuput, Dušan; Le Gall, Frederic; Marquais, Michel; Dechraoui, Marie Y; Molgo, Jordi | |
| Title | Ionic mechanisms involved in the nodal swelling of myelinated axons caused by marine toxins | |
| Type | članek | |
| Source | Cell Mol Biol Lett | |
| Vol. and No. | Letnik 7, št. 2 | |
| Publication year | 2002 | |
| Volume | str. 317-21 | |
| Language | eng | |
| Abstract | This review describes the ionic mechanisms involved in the nodal swelling of frog myelinated axons caused by specific marine neurotoxins (ciguatoxins, brevetoxins, Conus consors toxin and equinatoxin-II), analysed using confocal laser scanning microscopy. We have focussed on toxins that either target neuronal voltage-dependent Na+ channels, or that form cationselective pores and indirectly affect the functioning of the Na+-Ca++ exchanger. | |
| Descriptors | AXONS CIGUATOXIN CNIDARIAN VENOMS MARINE TOXINS NEUROTOXINS CATIONS RANVIER'S NODES SODIUM CHANNELS RANIDAE |