Author/Editor | Podnar, T; Runovc, F; Kordaš, M | |
Title | Simulation of cardiovascular physiology: the diastolic function(s) of the heart | |
Type | članek | |
Source | Comput Biol Med | |
Vol. and No. | Letnik 32, št. 3 | |
Publication year | 2002 | |
Volume | str. 363-77 | |
Language | eng | |
Abstract | The cardiovascular system was simulated by using an equivalent electronic circuit. Four sets of simulations were performed. The basic variables investigated were cardiac output and stroke volume. They were studied as functions (i) of right ventricular capacitance and negative intrathoracic pressure; (ii) of left ventricular relaxation and of heart rate; and (iii) of left ventricle failure. It seems that a satisfactory simulation of systolic and diastolic functions of the heart is possible. Presented simulations improve our understanding of the role of the capacitance of both ventricles and of the diastolic relaxation in cardiovascular physiology. | |
Descriptors | HEART MYOCARDIAL CONTRACTION DIASTOLE COMPUTER SIMULATION MODELS, CARDIOVASCULAR VENTRICULAR FUNCTION, RIGHT VENTRICULAR FUNCTION, LEFT VENTRICULAR DYSFUNCTION, LEFT SYSTOLE STROKE VOLUME CARDIAC OUTPUT |