Author/Editor | Lacković, I; Magjarević, R; Kovačič, D; Serša, G; Miklavčič, D | |
Title | Assessment of tumor tissue electroporation in vivo using electrical impedance | |
Type | članek | |
Source | IFMBE Proc | |
Vol. and No. | Letnik 3, št. 1 | |
Publication year | 2002 | |
Volume | str. 130-1 | |
Language | eng | |
Abstract | In our study we examined the possibilities of using electrical impedance spectrometry as a technique for the assessment of tumor tissue electroporation in vivo. We analyzed and compared, for three different pulsing protocols, the relationship between anti-tumor effectiveness of electrochemotherapy with bleomycin in mice tumor model and electrical impedance measured immediately after electroporation. The results of our study indicate that although we found impedance differences between various pulsing protocols, it was not possible to correlate them with anti-tumor effectiveness. Keywords: bioimpedance, electroporation, electro- chemotherapy, electric pulse parameters, bleomycin. | |
Descriptors | SARCOMA, EXPERIMENTAL BLEOMYCIN DRUG DELIVERY SYSTEMS ELECTROPORATION ELECTRIC IMPEDANCE MICE, INBRED C57BL |