Author/Editor     Lacković, I; Magjarević, R; Kovačič, D; Serša, G; Miklavčič, D
Title     Assessment of tumor tissue electroporation in vivo using electrical impedance
Type     članek
Source     IFMBE Proc
Vol. and No.     Letnik 3, št. 1
Publication year     2002
Volume     str. 130-1
Language     eng
Abstract     In our study we examined the possibilities of using electrical impedance spectrometry as a technique for the assessment of tumor tissue electroporation in vivo. We analyzed and compared, for three different pulsing protocols, the relationship between anti-tumor effectiveness of electrochemotherapy with bleomycin in mice tumor model and electrical impedance measured immediately after electroporation. The results of our study indicate that although we found impedance differences between various pulsing protocols, it was not possible to correlate them with anti-tumor effectiveness. Keywords: bioimpedance, electroporation, electro- chemotherapy, electric pulse parameters, bleomycin.
Descriptors     SARCOMA, EXPERIMENTAL
BLEOMYCIN
DRUG DELIVERY SYSTEMS
ELECTROPORATION
ELECTRIC IMPEDANCE
MICE, INBRED C57BL