Author/Editor		Repše, Stane
Title		Endokrini tumoprji trebušne slinavke - naša kazuistika
Translated title		Endocrine tumours of the pancreas - own experience
Type		članek
Source		In: Pleskovič A, editor. Zbornik simpozija Kirurgija trebušne slinavke; 2002; Ljubljana. Ljubljana: Kirurška klinika, Klinični oddelek za abdominalno kirurgijo,
Publication year		2002
Volume		str. 125-34
Language		slo
Abstract		Background. Due to small size, heterogeneous entities and sometimes unrealiable or even unsuccessful preoperative localisation endocrine pancreas tumours (EPTJ represent a serious surgical problem. Patients and methods. Retrospective analysis of our-own series of 35 EPT patients: 26 insulinomas, 3 carcinoids, 2 gastrinomas, 2 glucagonomas, 1 somatostatinoma and 1 nonfunctioning endocrine tumour. Type of surgery performed: insulinoma enucleation 16-times, left pancreatectomy 1 1-times, pancreatoduodenectomy 3-times, segmental (central) pancreas resection once, tumour resection without pancreas resection (gastrinoma and glucagonoma) twice, right hepatectomy (metastases of gastrinoma) once. In four patients with malignant insulinomas and a female patient with carcinoid liver metastases were resected simultaneously. Results. There was no case of postoperative death. In 3 patients with enucleation of insulinoma from the head of pancreas secretion with excessive amylase values persisted in the side of drainage for a longer time, but it stopped spontaneously. ln 4 patients percutaneous drainage of intraabdominal collection was necessary. One female patient developped pulmonary embolism. In 4 EPT patients recurrency occurred one to 8 years aher the first operation. All 4 patients underwent several operations and died due to tumour progression. There is no follow-up for 3 patients with malignant insulinoma with liver metastases (not Slovene residents). Conclusion. Accurate preoperative EPT localisation is the basis for successful surgery. Benign endocrine tumours should be enucleated, malignant ones require resection in the healthy tissue and removal of the metastases.
Descriptors		PANCREATIC NEOPLASMS ADENOMA, ISLET CELL CARCINOMA, ISLET CELL INSULINOMA GLUCAGONOMA GASTRINOMA NEUROENDOCRINE TUMORS SLOVENIA