Author/Editor		Pišljar, Marko
Title		Ocena vala P300 v dveh kliničnih skupinah bolnikov s Parkinsovo boleznijo: s prevladujočim tresenjem in hipokinezo ter rigidnostjo
Type		članek
Source		In: Repovš G, Gams M, Detela A, editors. Informacijska družba IS'2002: Kognitivna znanost. Zbornik C 5. mednarodne multi-konference; 2002 okt 14-18; Ljubljana. Ljubljana: Institut Jožef Stefan,
Publication year		2002
Volume		str. 197-200
Language		slo
Abstract		Mild to moderate cognitive dysfunction is a frequent complaint of patients with Parkinson's disease, though the clinical picture of dementia is rarely reported. The development of cognilive deficits seams to be associated with hypokinesia and rigidy rather than tremor. In our study, auditory ERP were used to confirm cognitive alterations in two groups of non-demented patients with idiopathic Parkinson * disease. Mini mental test was performed to exclude clinical picture of dementia. Patients were classified according to the Hoehn-Yahr and Webster scale. The Beck depression score in Parkinson's patient was assessed Auditory event related potentials were recorded using the "oddball" paradigm. The waves NI00, P200, N200 and P300 were recorded and their latencies and amplitudes measured The P300 lalencies in both patients group were significan tly longer (p<0,05), than in the controlgroup. P3001atency was longer in non tremorgroup. There were no significant statistical differences in latencies between the both groups. All patients had normal NI00 latency. Significant decline of P300 amplitude was found only in non-tremor group. (p<0,001).
Descriptors		PARKINSON DISEASE EVENT-RELATED POTENTIALS, P300 EVOKED POTENTIALS TREMOR COGNITION DISORDERS HYPOKINESIA