Author/Editor		Caumo, Francesca; Manfrin, Erminia; Bonetti, Franco; Pinali, Lucia; Procacci, Carlo
Title		Radiologic-pathologic correlation of the mammographic findings retrospectively detected in inflammatory breast cancer: usefulness in clinical practice
Translated title		Klinično koristna retrospektivna primerjava radioloških in patomorfoloških sprememb pri vnetnem raku dojke
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 36, št. 4
Publication year		2002
Volume		str. 275-80
Language		eng
Abstract		Background. The aim of this study was to describe the clinical, mammographical and pathological characteristics of inflammatory carcinoma. Patients and methods. Clinical, mammographical and histological sections of twenty-two women (age range 28-60 years) were reviewed. The examinations had been performed over a period of four years. Results. The clinical findings were: erythema, edema, thickening of the skin and breast heat in ten patients; palpable mass in nine patients; nipple discharge in one patient; absent in two patients. Pathological findings were: tumor emboli in the dermal lymphatics in eight patients; tumor emboli in the vessels in ten patients; tumor emboli both in the dermal lymphatics and in the vessels in four patients. The radiologic findings were: skin thickening trabecular thickening and blurring of structure in ten patients (common presentation); mass in nine patients; malignant-type calcifications in two patients (uncommon presentation); absent in one patient. The follow-up examination (eighteen months) detected that only one patient with common presentation of inflammatory carcinoma had no local or systemic recurrence against eightpatients with uncommon presentation. Conclusions. The clinical and mammographical aspects, which suggest the presence of an inflammatory carcinoma, occur only in 45.4% of the patients. The radiological aspect seems to correlate with the different prognosis of the tumour, resulting in a better prognosis in those with an uncommon aspect.
Summary		lzhodišča. Namen naše študije je bil opisati klinične, mamografske in patomorfološke značilnosti vnetnega raka dojke. Bolniki in metode. Pregledali smo klinične in mamografske značilnosti pa tudi patomorfološke slike 22 bolnic starih od 28 do 60 let, z vnetnim rakom dojke, ki so bile obravnavane v obdobju štirih let. Rezultati. Klinične značilnosti so bile: pri desetih bolnicah kožna rdečina, edem in zadebelitev ter vroča dojka; pri devetih bolnicah je bila tipna zatrdlina; pri eni bolnici izcedek iz bradavice; brez izrazitih kliničnih znakov pa sta bili dveh bolnici. Patomorfološke značilnosti so bile: pri osmih bolnicah embolizmi v kožnih limfatičnih žilah; pri desetih bolnicah tumorski embolizmi v krvnih žilah; pri štirih bolnicah tumorski embolizmi v limfafiičnih in krvnih žilah. Običajne radiološke spremebe so bile: pri desetih bolnicah zadebelitev kože, trabekularna zgostitev in zabrisanost strukture mamarnega tkiva. Neobičajne radiološke spremembe pa so bile: pri devetih bolnicah tumorska masa in pri dveh bolnicah maligni tip kalcinacij. Pri eni bolnici nismo našli radioloških sprememb. Po 18 mesecih sledenja bolezni samo ena bolnica iz skupine z običajnimi radiološkimi spremembami ni imela lokalne ali sistemske ponovitve bolezni, ter osem bolnic iz skupine z neobičajnimi radiološkimi spremembami. Zaključki. Običajne klinične in mamografske značilnosti, opisovane pri vnetnem raku dojke, se javljajo le pri 45,4% bolnic. Naša študija kaže, da so radiološke spremembe povezane z različno prognozo bolnic. Tiste z neobičajnimi radiološkimi spremembami za vnetni rak dojke imajo boljšo prognozo.
Descriptors		BREAST NEOPLASMS MAMMOGRAPHY NEOPLASM CIRCULATING CELLS EMBOLISM