| Author/Editor | Gruden, Kristina | |
| Title | Tehnologija genskih mikromrež in njihova uporaba v farmaciji | |
| Translated title | DNA microarrays technology and its application in pharmacy | |
| Type | članek | |
| Source | Farm Vestn | |
| Vol. and No. | Letnik 53, št. 1 | |
| Publication year | 2002 | |
| Volume | str. 11-5 | |
| Language | slo | |
| Abstract | DNA microarray technology enables analysis of thousands of genes in parallel, getting towards genome scale expression measurement. Till now it has been possible to follow only a few genes at a time, which contributed significantly to the understanding of development and progress of different diseases. Consequently, the DNA microarray technology that enables us to follow the gene expression profile of a tissue has opened a way for development of new tools in diagnostics and prognosis of the disease, in addition to application of the new technology in search for new drugs. | |
| Summary | Tehnologija genskih mikromrež omogoča hkratno analizo izražanja tisoč genov in se s tem bliža spremljanju izražanja genov na nivoju celega genoma. Do razvoja te tehnike je bilo možno spremljati izražanje le nekaj že poznanih genov hkrati, kar je pripomoglo k razumevanju razvoja in poteka različnih boleznih. Posledično je uporaba tehnologije genskih mrež, s katerimi spremljamo cel vzorec izražanja genov v nekem tkivu, odprla pot razvoju novih orodij v diagnostiki in prognostiki najrazličnejših bolezni, na različne načine pa se uporablja tudi pri iskanju novih zdravil. | |
| Descriptors | TECHNOLOGY, PHARMACEUTICAL GENE EXPRESSION GENE LIBRARY DRUG APPROVAL OLIGONUCLEOTIDE PROBES |