Author/Editor		Bilban, M; Vrhovec, S; Zorec-Karlovšek, M
Title		Krvni pokazatelji škodljive rabe alkohola
Type		članek
Source		In: Zbornik referatov. 5. mednarodna konferenca Globalna varnost; 2002 okt 6-9; Portorož. Ljubljana: Zavod za varstvo pri delu,
Publication year		2002
Volume		str. 1-9
Language		slo
Abstract		The biological, clinical and social effects of alcohol abuse have long made evident the need for objective and specific markers for alcohol-related diseases and for early detection of alcohol consumers at risk. Alcohol abusers may exhibit several clinico-chemical alterations, some of which have been used as markers of alcoholism, e.g.: gama glutamyltransferase (GGT), aspartat aminotransferase (AST), alanin aminotransferase (ALT), and mean corpuscular volume (MCV). All of the markers available thus far have two drawbacks: either they are indicators of disease in a paricular organ, with poor specifity for different etiological possibilities, or they are not sensitive enough to detect abuse before the stage of organic complications. During the last decade a new diagnostic marker -CDT (carbohydrate-deficient transferrin) has been introduced that appears to fulfill important clinical criteria. It is apparently dependent on ethanol or its metabolism, it appears in serum after regular high alcohol intake.
Descriptors		ALCOHOL DRINKING ALCOHOL, ETHYL GAMMA-GLUTAMYLTRANSFERASE ASPARTATE AMINOTRANSFERASE ALANINE AMINOTRANSFERASE ERYTHROCYTE INDICES TRANSFERRIN