Author/Editor		Kaplanovič, Milena; Korpič, Aida
Title		Multifokalna elektroretinografija pri bolnikih z boleznijo makule in zdravih preiskovancih
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		2002
Volume		str. 53
Language		slo
Abstract		BACKGROUND. Multifocal electroretinography (mfERG) is a new method for imaging the functional map of electric activity in a retina divided into fields, thus offering a more precise depiction of the very small part of the retina which is of extreme importance for eyesight: the fovea. The Ganzfeld ERG and pattern electroretinography (PERG) methods used to date measure a stimulated retina's sum of bioelectric responses, which limits their applicability in localised retinal disorder diagnosis. Multifocal electroretinography thus offers a useful complement to other electrophysiological methods, which is particularly important in differential diagnostics of maculopathies and their discemment from optic nerve neuropathies. AIM. In 2001 the International Society for Clinical Electrophysiology of Vision (ISCEV) issued guidelines for the imaging and the definition of normative values for mfERG, thus laying down the conditions that would allow for better comparison of results between laboratories worldwide. The aim of the present paper is to define our own normative values for the new method with healthy volunteers in line with ISCEV guidelines. The authors' sim was also to assess the applicability of mfERG in early diagnosis of the most frequent disorders to the fovea (Stargardt's macular dystrophy, Best macular dystrophy, age related macular degeneration). HYPOTHESIS. Simultaneous multifocal stimulation of the retina and response measurement in individual fields allow for earlier and more precise objective diagnosis of disease-related alterations to the macula compared against the established electrophysiological methods such as Ganzfeld ERG and pattern electroretinography. METHODS. The research comprised of mfERG imaging in 20 healthy volunteers (10 males, 10 females, age 20 to 28; mean female age 23.9, mean male age 25.8). (Abstract truncated at 2000 characters).
Descriptors		MACULAR DEGENERATION ELECTRORETINOGRAPHY VISUAL ACUITY FLUORESCEIN ANGIOGRAPHY ELECTROOCULOGRAPHY SCOTOMA