Author/Editor		Stantić-Pavlinić, Mirjana; Xiao, Lihua; Glaberman, Scott; Lal, Altaf A; Oražen, Toni; Rataj-Verglez, Aleksandra; Logar, Jernej; Berce, Ingrid
Title		Cryptosporidiosis associated with animal contacts
Type		članek
Source		Wien Klin Wochenschr
Vol. and No.		Letnik 115, št. 3-4
Publication year		2003
Volume		str. 125-7
Language		eng
Abstract		Transmission of Crypfosporidium sp. within the general public was studied. We were looking for a possible risk of infection associated with animal contacts. Investigation of the animal contacts of affected individuals led to the formulation of the hypothesis that animals are a source of cryptosporidiosis. The research was done in the Region of Ljubljana, an area with 587,000 inhabitants during a period of three years. Stool specimens of 338 persons with acute enteric diseases were positive for Cryptosporidium sp. Diagnosis was done with an immunofluorescence test and modified ZielNeelsen staining. Processing of statistical data was done with the medical software application EPI INFO 6. According to our questionnaire, direct contact with animals occurred in 49 of the 338 cases of cryptosporidiosis, and was more frequently registered in males (Odds ratio = 1.96). Subgenotyping analysis revealed the presence of two subgenotypes of Cryptosporidium parvum bovine (GPB and GP`) in humans. These data indicate that genetic heterogeneity in C. parvum bovine genotype exists in a localized area and that farm animals can be a source of infection.
Descriptors		CRYPTOSPORIDIOSIS CRYPTOSPORIDIUM CRYPTOSPORIDIUM PARVUM GENOTYPE DISEASE VECTORS FLUORESCENT ANTIBODY TECHNIQUE, DIRECT QUESTIONNAIRES