Author/Editor		Peklar, J; Tratar, F; Mrhar, A
Title		Stroškovna učinkovitost uvedbe Obrazca za naročilo antibiotika v Splošni bolnišnici Celje
Translated title		Cost effectiveness analysis of implementation of drug formulary for antimicrobials in General hospital Celje
Type		članek
Source		Farm Vestn
Vol. and No.		Letnik 52, št. 3
Publication year		2001
Volume		str. 251-8
Language		slo
Abstract		Increase of hospital infections became over past years one of the major problems in treatment of infections world-wide and also in Slovenia. Microbial agents producing hospital infections are becoming resistant to many antibiotics usually used in hospital settings. Moreover, the therapy is usually connected with high costs that are even increasing. General hospital Celje (GHC) decided to undertake a new approach towards antimicrobial treatment. In April 1998 they came up with guidelines for antimicrobial treatment and with an order form for prescribing antimicrobials. It was our aim to reveal whether these two interventions contribute significantly to the rational use of antimicrobials considering clinical and economic outcomes. We analysed the usage of antimicrobials from medicinal documentation at the Department of infectious diseases in a period of 1 month before introduction of order form for order of antimicrobials and after introduction. We presented results in DDD/100 BOD. In pharmacoeconomic study which was set from the hospital point of view we measured the costs of antimicrobial treatments. The usage of restricted antimicrobials in DDD/100 BOD has reduced for 64,0%. Costs of therapy has lowered after introduction of new antimicrobial approach for 37,4%. Time of treatment of patients has shortened for 27,2%. Introduction of new approach in antimicrobial treatment has achieved its purpose; it reduced usage of expensive and from microbial resistance threatened antimicrobials and at the same time it was also cost effective.
Summary		V zadnjih letih postaja v bolnišnicah v Sloveniji in po celem svetu problematika odpornih mikroorganizmov, ki povzročajo težke bolnišnične okužbe, vse hujša. Hkrati pa stroški protimikrobnega zdravljenja zaradi različnih vzrokov neprestano naraščajo. V okviru zajezitve neracionalnega predpisovanja protimikrobnih (PM) zdravil so v Splošni bolnišnici Celje (SBC) v mesecu aprilu 1998 uvedli Obrazec za naročilo antibiotika. Nas sta zanimala klinični in ekonomski vidik uvedbe tega restriktivnega ukrepa. Na osnovi medicinske dokumentacije bolnikov iz Oddelka za infekcijske bolezni in vročinska stanja SBC smo analizirali porabo PM zdravil v DDD/100 BOD v času enega meseca. S farmakoekonomsko študijo smo v enakem časovnem obdobju ocenili stroške zdravljenja pred uvedbo Obrazca za naročilo antibiotika in po njem ter rezultate izrazili v porabljenih sredstvih na 1 bolnika. Stroške smo vrednotili z vidika bolnišnice. Ugotovili smo, da se je poraba omejevanih PM zdravil (tistih, ki so na Obrazcu za naročilo antibiotika) v DDD/100 BOD zmanjšala za 64,0%. Stroški zdravljenja infekcijskih bolezni so po uvedbi racionalizacijskih ukrepov na izbranem oddelku upadli za 37,4%. Čas zdravljenja bolnikov pa se je v povprečju znižal za 27,2%. Racionalizacijski ukrepi na izbranem oddelku SBC so dosegli svoj namen; zmanjšali so porabo dragih in zaradi odpornosti mikroorganizmov potencialno ogroženih PM zdravil, ob tem pa so bili tudi stroškovno učinkoviti.
Descriptors		ANTIBIOTICS DRUG COSTS DRUG UTILIZATION PRESCRIPTIONS, DRUG BACTERIAL INFECTIONS COST-BENEFIT ANALYSIS COMMUNICABLE DISEASES HOSPITAL DEPARTMENTS LENGTH OF STAY HOSPITAL COSTS