Author/Editor		Špiclin, Polona; Gašperlin, Mirjana
Title		Vitamin C in koža
Translated title		Vitamin C and the skin
Type		članek
Source		Farm Vestn
Vol. and No.		Letnik 52, št. 4
Publication year		2001
Volume		str. 287-93
Language		slo
Abstract		Vitamin C has been used in cosmetic and pharmaceutical skin care products since it has many favorable effects on the skin. As an antioxidant agent, vitamin C can scavenge and destroy reactive oxidizing agents and other free radicals. Because of this capability it represents an important protection against UV induced damage. Vitamin C also improves the elasticity of the skin and reduces wrinkles by stimulating the synthesis of collagen. By suppressing the pigmentation the drug influences the complexion of the skin. The use of vitamin C in products is limited due to its low stability. It is more convenient to use vitamin C derivatives, for example ascorbyl palmitate and ascorbyl phosphate salts. Both derivatives demonstrate an improved chemical stability, but differ in hydro-lipophilic behaviour, which determines the ability of the drug to permeate the skin.
Summary		Vitamin C ima na koži mnogo ugodnih učinkov, zato se v zadnjem času pogosto pojavlja v kozmetičnih in farmacevtskih izdelkih za kožo. Kot antioksidant odstranjuje reaktivne kisikove spojine in druge proste radikale, zato predstavlja pomemben del zaščite kože pred UV sevanjem. Poleg tega vitamin C s stimulacijo sinteze kolagena izboljša elastičnost kože in zmanjša nastajanje gub, z zaviranjem pigmentacije pa vpliva na obarvanost kože. Vitamin C je za vgrajevanje v izdelke neprimeren, ker je zelo nestabilen. Smiselna je uporaba derivatov vitamina C, npr. askorbil palmitata ali soli askorbil fosfatov. Oba derivata imata izboljšano kemijsko stabilnost, razlikujeta pa se v hidro-lipofilnih lastnostih, ki določajo sposobnost prehajanja v kožo.
Descriptors		ASCORBIC ACID SKIN SKIN CARE SKIN AGING ANTIOXIDANTS COLLAGEN SKIN PIGMENTATION