Author/Editor		Urlep, D; Mičetić-Turk, D; Dolinšek, J
Title		Obravnava otrok s prehransko alegijo in bolezenskimi znaki v prebavilih
Translated title		Clinical approach to (treatment of) the child with gastrointetsinal manifestations of food allergy
Type		članek
Source		In: Gregorič A, editor. Nutritivna alergija. Farmakologija perinatalnega obdobja. Skrb za zdravje v prvem letu življenja. Zbornik predavanj 13. srečanje pediatrov v Mariboru z mednarodno udeležbo; 2003 apr 4-5; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		2003
Volume		str. 53-9
Language		slo
Abstract		Food allergy can manifest itself as a variety of gastrointestinal symptoms, signs and syndromes. The pathogenesis usually involves immune reactions of cell-mediated immunity, with only a minority of reactions being IgE mediated. The diagnostic approach to a patient with suspected food allergy and with signs of gastrointestinal involvement therefore requires a good knowledge of clinical syndromes of gastrointestinal allergy. The final diagnosis must be based on a thorough history, physical examination and elimination/provocation tests. Histologic examination of biopsy specimens taken from several regions of the gastrointestinal tract can be a valuable diagnostic tool. Treatment is based on an elimination diet. Highly hydrolysed formulas are recommended in infants and young children. Patients that are allergic to these hydrolysed formulas require amino-acid based formulas. It is very important that a diagnosis of food allergy is based on objective parameters. A falsely established diagnosis can lead to serious malabsorbtion, eating disorders and psychosocial problems. An overlooked diagnosis, however, presents an unnececary burden and can lead to serious disabilities in a child.
Descriptors		FOOD HYPERSENSITIVITY IMMUNITY, MUCOSAL IMMUNITY, CELLULAR DIETARY PROTEINS CHILD HYPERSENSITIVITY, IMMEDIATE EOSINOPHILIA ESOPHAGITIS GASTROENTERITIS PROCTOCOLITIS ENTEROCOLITIS PROTEIN-LOSING ENTEROPATHIES IMMUNOLOGIC TESTS