Author/Editor		Blacher, Silvia; Devy, Laetitia; Noel, Agnes; Foidart, Jean-Michel
Title		Quantification of angiogenesis on the rat aortic ring assay
Type		članek
Source		Image Anal Stereol
Vol. and No.		Letnik 22, št. 1
Publication year		2003
Volume		str. 43-8
Language		eng
Abstract		Image analysis is used to quantify angiogenesis on the rat aortic ring model. This technique allows to determine: (1) the aortic ring area and factor shape; (2) the number of microvessels, the total number of branching, the maximal microvessel length and the number of microvessels in function of the distance to the aortic ring; (3) the total number of isolated fibroblast-like cells and the number of fibroblast-like cells in function of the distance to the aortic ring. We show that this method is suitable to quantify spontaneous angiogenesis as well as to analyse a complex microvascular network induced by vascular endothelial growth factor (VEGF).
Descriptors		AORTA FIBROBLASTS NEOVASCULARIZATION, PHYSIOLOGIC ENDOTHELIUM, VASCULAR IMAGE PROCESSING, COMPUTER-ASSISTED CELLS, CULTURED ENDOTHELIAL GROWTH FACTORS RATS