Author/Editor | Blacher, Silvia; Devy, Laetitia; Noel, Agnes; Foidart, Jean-Michel | |
Title | Quantification of angiogenesis in rat aortic ring assay | |
Type | članek | |
Source | Image Anal Stereol | |
Vol. and No. | Letnik 20, št. Suppl 1 | |
Publication year | 2001 | |
Volume | str. 123-8 | |
Language | eng | |
Abstract | lmage analysis is used to quantify angiogenesis on the rat aortic ring model. This technique allows to determine: (1) the aortic ring area and its factor shape; (2) the number of microvessels, the total number of branching, the maximal microvessel length and the microvessel distribution; (3) the total number of isolated fibroblast-like cells and their distribution. We show that this method is suitable to quantify spontaneous angiogenesis as well as to analyse a complex microvascular network induced by vascular endothelial growth factor (VEGF). | |
Descriptors | AORTA NEOVASCULARIZATION, PHYSIOLOGIC FIBROBLASTS IMAGE PROCESSING, COMPUTER-ASSISTED RATS, INBRED F344 CELLS, CULTURED |