Author/Editor		Kanič, Vojko
Title		Metabolični sindrom
Translated title		Metabolic syndrome
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 42, št. Suppl 2
Publication year		2003
Volume		str. 23-8
Language		slo
Abstract		Metabolic syndrome is a cluster of diseases usually associated with abdominal obesity, hypertension, dyslipidemia and impaired glucose tolerance/type 2 diabetes. Insulin resistance with hyperinsulinemia plays a central role. The major features are increased risk of coronary artery disease and increased cardiovascular mortality. In addition, fibrinolysis is also impaired. It has been emphasised that because of the syndrome's multiple pathogenetic causes, its treatment should be comprehensive and directed against each single cause.
Summary		Metabolični sindrom je skupek bolezni, ki vključuje trebušni tip debelosti, sladkorno bolezen tipa 2 (ali moteno toleranco za glukozo), hipertenzijo in dislipidemijo. Osrednje dogajanje je povečana inzulinska rezistenca s hiperinzulinemijo. Kombinacija teh bolezni močno poveča tveganje za razvoj srčno-žilnih bolezni in umrljivost teh bolnikov. Oslabljena je fibrinoliza. Ker je dogajanje večvzročno, naj bo terapevtski pristop kompleksen in naravnan k vsem vzrokom.
Descriptors		INSULIN RESISTANCE OBESITY DIABETES MELLITUS, NON-INSULIN-DEPENDENT HYPERTENSION HYPERLIPIDEMIA HYPERINSULINEMIA CORONARY DISEASE