| Author/Editor | Petric, Vlasta; Benkovič, Alenka; Kološa, Ivana; Horvat, Mateja; Lopert, Anton; Volavšek, Metka; Kovačič, Srečko | |
| Title | Eozinofilija pri bolniku z ekstranodalnim limfomom T naravnih ubijalk - prikaz primera | |
| Translated title | A case of axtranodal NK/T cell lymphoma presenting with eosinophilia | |
| Type | članek | |
| Source | Zdrav Vestn | |
| Vol. and No. | Letnik 72, št. 5 | |
| Publication year | 2003 | |
| Volume | str. 271-3 | |
| Language | slo | |
| Abstract | Background. Eosinophilia can occur in extranodal NK/T cell lymphoma. Chronic hypereosinophilia from any cause is associated with endomyocardial fibrosis. Methods and material. This report includes on a patient with hypereosinophilia which was diagnosed and investigated nine months before the diagnosis of extranodal NK/T cell lymphoma (nasal type) of the larynx was confirmed by biopsy. He died wtth signs of heart failure 11 months after the first symptoms developed. Post mortem investigation revealed endomyocardial fibrosis as a result of chronic hypereosinophilia. Conclusions. To our knowledge eosinophilia has not previously been reported in extranodal NK/T cell lymphoma (nasal type). Therefore, this is considered to be a rare feature of the presented case. Investigation of the heart for potential silent complications of prolonged and severe eosinophilia has to be considered at an early stage, | |
| Summary | Izhodišča. Eozinofilija se lahko pojavi tudi pri ekstranodalnem limfomu T naravnih ubijalk (T/NU). Če je dolgotrajna, lahko vodi v okvaro srčne mišice. Bolniki in metode. Prikazujemo primer bolnika z eozinofilijo, ugotovljeno devet mesecev pred postavitvijo diagnoze ekstranodalnega limfoma T/NU grla. Bolnik je umrl zaradi srčne odpovedi 21 mesecev po prvih simptomih. Na obdukciji je bila ugotovljena fibroza endomiokarda kot posledica kronične eozinofilije. Zaključki. Eozinofilija pri ekstranodalnem limfomu T/NU še ni bila opisana, zato menimo, da gre za redek primer. Pri bolnikih z izrazito in dolgotrajno eozinofilijo je pomembno zgodnje odkrivanje okvare srca, ki je lahko asimptomatska. | |
| Descriptors | EOSINOPHILIA LYMPHOMA, T-CELL KILLER CELLS, NATURAL AGED PHARYNGEAL DISEASES NOSE NEOPLASMS HEART FAILURE, CONGESTIVE HERPESVIRUS 4, HUMAN |