Author/Editor		Muzlovič, Igor
Title		Vpliv kolonizacije traheje na bolnišnično pljučnico
Translated title		The influence of tracheal colonization on nosocomial pneumonia
Type		članek
Source		In: Lužnik-Bufon T, Gubina M, editors. Zbornik predavanj Bolnišnične okužbe 2003; 2003; Ljubljana. Ljubljana: Sekcija za klinično mikrobiologijo in hospitalne infekcije,
Publication year		2003
Volume		str. 55-66
Language		slo
Abstract		There are many well-known risk factors that contribute to a high incidence of hospital-acquired pneumonia. One of them is previous colonization of the gastrointestina! and upper respiratory tract. We conducted a prospective randomized clinical study on tracheal colonization and hospital pneumonia in an intensive care unit of the Department of Infectious Diseases over 10 years. Data were collected from all consecutive patients without current antibiotic therapy at the time of inclusion. We included 81 patients in to the study.Most frequent diagnoses were tetanus (63 patients), and encephalitis (15 patients), whereas 3 patients were treated for other illness. Mechanical ventilation was performed in 52 (64%) patients. Mean APACHE II score was 19.5 (range 12 to 24). The most common grampositive microorganism that colonized trachea was Staphylococcus aureus and the most common gramnegative microorganisms were Pseudomonas aeruginosa, Acinetobacter calcoaceticus, Klebsiella spp. and Enterobacter spp. Nosocomial pneumonia was found in 55 patients, and in 36 cases (65.5%) of them, HP was preceded with tracheal colonization. Mean latent period beiween tracheal colonization and nosocomial pneumonia was 2.8 days. The longest latent period was found in the patients colonized with Acinetobacter spp.
Descriptors		PNEUMONIA CROSS INFECTION TRACHEA INTENSIVE CARE UNITS TETANUS ENCEPHALITIS RESPIRATION, ARTIFICIAL APACHE