Author/Editor		Reberšek-Gorišek, Jelka; Berginc-Dolenšek, Anica; Beović, Bojana
Title		Prikaz bolnikov s hemoragično mrzlico z renalnim sindromom v širši novomeški, ljubljanski in mariborski regiji v letu 2002
Translated title		Case studies of 27 patients with hemorrhagic fever and renal syndrome in the Ljubljana, Novo mesto and Maribor regions in 2002
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 42, št. Suppl 1
Publication year		2003
Volume		str. 141-6
Language		slo
Abstract		The objective of this presentation of 27 patients with hemorrhagic fever and renal syndrome (HFRS) from the Ljubljana, Maribor, and Novo Mesto regions in 2002 is to depict the epidemiologic, clinical and laboratory features of HFRS caused by the Dobrava and Puumala viruses. The diagnosis of HFRS was confirmed serologically by specific IgG and IgM immunofluorescent and enzyme-linked immunosorbent assay (ELISA). The most signifieant clinical features of infections with the two viruses include high fever, headache, pain, acute renal insufficiency and low platelet count. Analysis of obtained data showed that the course of the Puumala virus infection is milder than that caused by the Dobrava virus. However, severe clinical courses were observed as well. Other clinical Features were less significant.
Summary		S predstavitvijo 27 bolnikov s hemoragično mrzlico z renalnim sindrom v novomeški, ljubljanski in mariborski regiji v letu 2002, želijo avtorice prikazati epidemiološke, klinične in laboratorijske značilnosti hemoragične mrzlice z renalnim sindromom, povzročene z Dobrava in Puumala virusom. Diagnoza hemoraške mrzlice z renalnim sindromom je bila potrjena z dokazom specifičnih protiteles IgG in IgM po imunofluorescenčni in encimskoimunski metodi. Vodilne klinične značilnosti pri obeh virusih so bile: visoka telesna temperatura, glavobol, bolečine v mišicah, sklepih, ledveno in/ali v trebuhu, ledvična okvara in trombocitopenija. Ostali klinični znaki pa so bili manj značilni. Potek okužbe s Puumala virusom je videti nekoliko milejši kot potek bolezni, ki jo povzroča Dobrava virus, vendar so tudi pri okužbi s Puumala virusom znani hujši primeri. Pojav hujših primerov hemoragične mrzlice z renalnim sindromom v Sloveniji nakazuje potrebo po specifičnem zdravljenju bolnikov.
Descriptors		HEMORRHAGIC FEVER WITH RENAL SYNDROME