Author/Editor		Vogler, A
Title		Primerjava dinoprostona in karboprosta za predoperativno dilatacijo cervikalnega kanala pred umetno prekinitvijo nosečnosti pri primigravidah
Translated title		Preoperative cervical dilatation prior to early pregnancy termination in primigravid women: a comparison of carboprost and dinoprostone
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 60, št. 12
Publication year		1991
Volume		str. 517-9
Language		slo
Abstract		120 primigravid women due to undergo early pregnancy termination (6.5 to 100) were randomly selected for prostaglandine application 6 hours prior to vacuum aspiration. Carboprost (0.25 mg) was applicated intramusculary to 60 women, and 0.5 mg of dinoprostonein the form of intracervical gel was applicated to the other 60 women. Before application all women had the cervix closed, i. e. dilated less tha 3 mm. After 6 hours a marked cervical softening and dilatation was noticed in all 120 cases (100 per cent ). In the dinoprostone group of women, dilataton was statistically significantly greater than in a charboprost group. In 44 (73.3 per cent ) women in the carboprost group gastrointestinal side effects occurred, whereas in the dinoprostone group gastrointestinal side effects were observed in 28 (46.7 per cent ) cases. After prostaglandine application there were no significant changes in blood pressure and body temperature. During the procedure there were no complications. We can conclude that application of prostaglandins is a very effective method for preoperative dilatation and prevention of cervical and uterine injury wich can occur in mechanical dilatation. Side effects occur quite often, especially when systemic application is used, but can be successfully treated with apropriate medication. Preoperative application of prostaglandine should be used always in primigravid women when pregnancy termination is desired.
Descriptors		ABORTION, INDUCED CERVIX UTERI CARBOPROST DINOPROSTONE PREGNANCY