Author/Editor		Vrtačnik-Bokal, Eda; Pinter, Bojana
Title		Klamidija trahomatis in humana papiloma virusa 16 in 18 pri mladostnicah
Translated title		Chlamydia trachomatis and humanpapilloma virus 16 and 18 in adolescents
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 72, št. Suppl 2
Publication year		2003
Volume		str. II-31-3
Language		slo
Abstract		Background. Adolescents represent a risk group for sexually transmitted infections. The aim of this study was to find the incidence of Chlamydia trachomatis (CT) and human papillomavirus (HPV) in adolescents. Additionally, we wanted to know, whether the prevalence of CT was so high that antibiotic prophylaxis would be appropriate before termination of pregnancy. Patients and methods. In the study 200 adolescents aged 15 to 19 years were enrolled: 100 came for termination of pregnancy and 100 for a contraceptive method. In all cases the cervical smears were taken for culture and direct immunofluorescence (DIF) for CT. The cervical smear was used also for hybridiyation test for the detection of HPV 16 and HPV 18. Serologic analysis for hepatitis B, HIV and syphilis were done in all cases. Results. CT was isolated in 6% in the first and in 4% in the second group Using DIF method CT was confirmed in 7% in the first and in 4% in the second group. HPV 16 or 18 was positive in 26% in the first and in 13% in the second group. We did not find any case of syphilis, HIV and hepatitis. Conclusions. A 6% prevalence of CT justifies the use of antibiotic prophylaxis before termination of pregnancy.
Summary		Izhodišča. Mladostniki sodijo v skupino z zvečanim tveganjem za spolno prenosljive okužbe. Namen naše študije je bil ugotoviti prevalenco klamidije trahomatis (KT) in genotipov humanega virusa papiloma z visokim tveganjem (HPV), tipa 16 in 18. Dodatno smo želeli izvedeti, ali je prevalenca okužbe s klamidijo trahomatis tako velika, da opravičuje antibiotično profilakso pred zgodnjo prekinitvijo nosečnosti. Preiskovanke in metode. V raziskavo smo vključili 200 mladostnic, starih od 15 do 19 let. V prvo skupino smo vključili 100 mladostnic, ki so prišle zaradi zgodnje prekinitve nosečnosti, v drugo skupino pa naslednjih 100 preiskovank, ki so prišle zaradi kontracepcije. Pri vseh preiskovankah smo odvzeli brise iz materničnega vratu za osamitev KT v kulturi in za določitev KT z direktno imunoflorescenco (DIF). Bris materničnega vratu smo uporabili tudi za določitev HPV 16 in HPV 18 s hibridizacijskim testom. Pri vseh preiskovankah smo opravili tudi serološke analize za hepatitis B, HIV in sifilis. Rezultati. KT smo osamili pri 6% preiskovank v prvi skupini in pri 4% preiskovank v drugi skupini. Z uporabo metode DIF je bila potrjena okužba s KT pri 7% preiskovank v prvi skupini in pri 4% preiskovank v drugi skupini. Okužba s HPV 16 ali 18 je bila v 26% prisotna v prvi skupini in v 13% v drugi skupini. Sifilisa, HIV-a in hepatitisa B nismo potrdili v nobeni skupini. Zaključki. Šestodstotna prevalenca okužbe s KT opravičuje antibiotično profilakso pred zgodnjo prekinitvijo nosečnosti pri mladostnicah.
Descriptors		SEXUALLY TRANSMITTED DISEASES CHLAMYDIA TRACHOMATIS PAPILLOMAVIRUS, HUMAN ADOLESCENCE VAGINAL SMEARS ABORTION, LEGAL CONTRACEPTIVES, ORAL, HORMONAL SEX BEHAVIOR